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WHY SOME PEOPLE GET HIGH ON THC EDIBLES & SOME DON'T: THE TRUTH BEHIND BEING "EDIBLOCKED"

So you tried a cannabis edible—maybe even a few—and waited patiently for that euphoric high everyone talks about… but nothing happened. You’re not alone, and you're definitely not broken. The phenomenon of not feeling the effects of THC edibles is real, and it even has a name: Ediblocked.


Let’s break down why some people just don’t get high from edibles and what your genetics and liver health have to do with it.

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🍬 What Does It Mean to Be Ediblocked?

Being Ediblocked means your body doesn’t experience the psychoactive effects of THC through edibles, even at doses that affect others. You might feel something, like a little relaxation or sleepiness, but you never really hit that full-body edible high people rave about.


This frustrating experience is often tied to how your body processes THC—and much of that comes down to your genetic makeup.


🧬 It’s All in Your Genetics

Your genetic code controls everything from how you look to how your liver metabolizes drugs. When you consume THC in edible form, your liver plays a critical role. Here's why:

  • Edibles must be digested and metabolized by the liver before THC becomes active in your bloodstream.

  • Once in the liver, THC is converted into 11-hydroxy-THC, a metabolite that’s much more potent and longer-lasting than regular THC (the kind you inhale).

  • This process depends heavily on a group of liver enzymes called cytochrome P-450 enzymes, particularly CYP2C9.


If your body produces low levels of these enzymes—or they don’t function effectively due to your genetics—you may not efficiently convert THC into its active form. As a result, the effects are weak or nonexistent.


💊 Factors That Can Affect How Edibles Work

Aside from genetics, several biological and lifestyle factors may influence whether edibles work for you:


🔬 Liver Enzyme Activity

  • Your liver enzymes, especially CYP2C9, determine how well you convert THC into 11-hydroxy-THC.

  • Some people have genetic variations that make this process inefficient, leaving them “Ediblocked.”


🥑 Body Fat Percentage

  • THC is fat-soluble, meaning it binds to fat in the body.

  • People with higher body fat might store more THC, affecting how long it takes to feel the effects—or how intense they are.


Metabolic Rate

  • A faster metabolism may lead to quicker but shorter-lived effects.

  • Slower metabolism might delay the high but make it last longer.


💊 Tolerance

  • Frequent cannabis use can lead to higher tolerance, requiring larger doses to feel the same effects.

  • A tolerance break can reset your system and make edibles more effective.


🥗 Digestive Health

  • Conditions like IBS or poor gut absorption can interfere with THC uptake.

  • Eating edibles with food can delay the onset but often extends the high.


🌡️ Quality & Potency

  • Lab-tested, well-made edibles are more consistent in THC dosage.

  • Homemade or poorly stored edibles may degrade or vary in potency.

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🚫 Watch What You Eat (and Take)

Did you know certain foods and medications can interfere with how your body processes THC? Grapefruit, for example, can inhibit liver enzymes and lead to unpredictable or intensified effects. Other drugs may speed up or slow down the same enzymes that metabolize THC, affecting how strong or weak your high feels.


🧃 Not All Cannabinoids Get You High

  • Delta 9 THC and Delta 8 THC are both psychoactive and can produce a high.

  • CBD and CBG, however, are non-psychoactive and will not get you high, though they may support relaxation, mood, or pain relief.


🐢 Start Low & Go Slow

Edibles can be powerful—and unpredictable—especially for first-timers or those with slow metabolisms. Always:

  • ✅ Start with a low dose (5-10mg THC)

  • ⏱️ Wait at least 2 hours before considering more

  • 🌱 Choose lab-tested, high-quality products


Your friend’s sweet spot might knock you off your feet—or leave you feeling nothing. Our bodies are beautifully unique, and how we respond to cannabis is no different. Just because something didn’t work once doesn’t mean it never will. It may take experimentation, education, and patience to find what works for you.


🧘‍♀️ Final Thoughts

If you’ve ever felt left out of the edible experience, you’re not alone—and there’s usually a scientific explanation behind it. Being Ediblocked doesn’t mean cannabis isn’t for you—it just means you may need to explore other methods (like vaping, tinctures, or beverages) or learn more about how your body responds to THC.


Slow & steady wins the race—especially with anything psychoactive. 💚

Need help navigating THC, CBD, or finding the right product for your body? At SunKissed Greenz, we’re here to guide you through every step of your wellness journey—because there’s no one-size-fits-all when it comes to feeling good. 🌿

 
 
 

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These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease

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